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IMPACT OF PHOTODYNAMIC THERAPY ON ORAL HEALTH IN PATIENTS UNDERGOING FIXED ORTHODONTIC TREATMENT: A RANDOMIZED
N Berisha1, E Veseli2, F Sahiti3
11Department of Orthodontics, Dental School, Faculty of Medicine, University of Prishtina, Kosovo.
Georgian Medical News
|July 30, 2025
Summary
Photodynamic laser therapy (PDT) significantly improves gingival health and reduces dental plaque in patients with fixed orthodontic appliances. PDT offers a valuable addition to standard oral hygiene for managing orthodontic-related gingivitis and plaque.
Area of Science:
- Periodontology
- Orthodontics
- Biophotonics
Background:
- Patients with fixed orthodontic appliances (FOA) often experience increased gingival inflammation and dental plaque accumulation.
- Maintaining oral hygiene can be challenging with FOA, necessitating adjunctive therapeutic strategies.
Purpose of the Study:
- To evaluate the efficacy of photodynamic laser therapy (PDT) in improving gingival health and reducing dental plaque in patients undergoing orthodontic treatment with FOA.
- To assess the effects of PDT at different time points during orthodontic treatment.
Main Methods:
- A randomized controlled trial was conducted with 60 patients with FOA, divided into a control group and a PDT group (methylene blue plus laser activation).
- Gingival Index (GI) and Dental Plaque Index (DPI) were used to assess oral conditions at baseline (T1) and after 30 days (T2).
- Statistical analysis included independent samples t-tests and repeated measures ANOVA.
Main Results:
- The PDT group showed a significant improvement in gingival condition, with a decrease in inflammation and an increase in normal gingival tissue from T1 to T2.
- Dental plaque levels also significantly decreased in the PDT group by T2.
- Statistical analysis revealed significant differences in both GI and DPI between the groups over time (p<0.05).
Conclusions:
- Photodynamic laser therapy (PDT) with methylene blue is effective in improving gingival health and reducing dental plaque in patients with fixed orthodontic appliances.
- PDT can serve as a beneficial adjunct to conventional oral hygiene methods for managing gingivitis and plaque during orthodontic treatment.

