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Updated: Jul 8, 2026

Synthetic, Multi-Layer, Self-Oscillating Vocal Fold Model Fabrication
Published on: December 2, 2011
Reply to comment on "Feasibility of improving vocal fold pathology image classification with synthetic images
Iman Khazrak1, Shahryar Zainaee2, Mostafa M Rezaee3
1Department of Computer Science, Bowling Green State University, Bowling Green, 43403, OH, USA. ikhazra@bgsu.edu.
Abstract:
In response to the recent commentary on our pilot study using denoising diffusion probabilistic models (DDPMs) for vocal fold structural pathology image augmentation, we clarify our study's rationale and methods. The original work evaluated the feasibility of synthetic image generation to address data scarcity and imbalance. We affirm that several concerns raised were already addressed and note that statistical testing was not conducted due to the study's exploratory nature. Additional clarifications are provided in this letter to address points raised in the commentary and to outline directions for future research.

