Phaco + iStent implant learning curve in a teaching hospital
Diogo Bernardo Matos1,2, Rafael Correia Barão1,2, Nuno Pinto Ferreira1,2
1Serviço de Oftalmologia - Unidade Local de Saúde Santa Maria, Centro Hospitalar Universitário Lisboa Norte - Hospital Santa Maria, Lisboa, Portugal.
European Journal of Ophthalmology
|July 31, 2025
Summary
The iStent inject W procedure, combined with cataract surgery, offers a safe and effective way to reduce intraocular pressure (IOP) in glaucoma patients. Surgeons found it a fast-learning procedure with a good safety profile.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Minimally Invasive Procedures
Background:
- The iStent inject W is a device for alternative aqueous humor drainage to reduce intraocular pressure (IOP).
- Existing international reports support its efficacy, but data on the early learning curve is limited.
Purpose of the Study:
- To evaluate the learning curve, safety, and efficacy of the iStent inject W during its initial implementation.
- To assess surgical time, complications, and postoperative IOP reduction in early cases.
Main Methods:
- A retrospective study of the first 6 iStent inject W implants by 6 surgeons in a tertiary hospital.
- Procedures were combined with cataract surgery (phaco + iStent inject W).
- Surgical time, complications, and IOP were monitored preoperatively and up to 90 days postoperatively.
Main Results:
- Surgical time decreased by 8.5 minutes across the learning curve for the first 36 patients.
- Mean preoperative IOP of 21.81 mmHg reduced to 16.00 mmHg at 1 month (a 26.64% decrease), with fewer medications needed.
- Trabecular meshwork hemorrhage was the most common intraoperative complication; no secondary interventions were required.
Conclusions:
- The iStent inject W procedure is perceived as a fast-learning, safe option for glaucoma management.
- The combined cataract surgery and iStent inject W approach significantly reduces IOP, offering a valuable treatment for glaucoma patients.


