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Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
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Lactylation: A New Metabolic Signature of Sepsis-Related Cardiac Dysfunction

Nahum F Arefeayne1,2, Jennifer Q Kwong2,3

  • 1Graduate Program in Biochemistry, Cell and Developmental Biology, Graduate Division of Biological and Biomedical Sciences, Emory University, Atlanta, GA (N.F.A.).

Circulation Research
|July 31, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Editorialscardiomyopathiesheart diseasesmitochondriamorbiditysepsis

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Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
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