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Evaluation of atomized tranexamic acid (TXA) for pediatric epistaxis

Kayla White1, David Rodriguez1, Kara Quaney1

  • 1Children's Health™ Children's Medical Center, Dallas, TX, United States of America.

The American Journal of Emergency Medicine
|July 31, 2025
PubMed
Summary

No abstract available in PubMed .

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Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
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Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
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