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Related Concept Videos

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Tooth Anatomy

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The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
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Teeth01:15

Teeth

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Osteoclasts in Bone Remodeling01:31

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
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Classification of Epithelial Tissues: Overview01:22

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Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
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Classification of Bones01:18

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The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
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Updated: Sep 13, 2025

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
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Redefining the void: A novel classification for internal resorption in human teeth.

Shishir H Singh1, Anuprita S Gadkari1, Rajesh S Podar1

  • 1Department of Conservative Dentistry and Endodontics, Terna Dental College, Navi Mumbai, Maharashtra, India.

Journal of Conservative Dentistry and Endodontics
|August 1, 2025
PubMed
Summary
This summary is machine-generated.

This study classifies internal root resorption, a tooth tissue loss condition. It categorizes lesions by location and extent for better diagnosis and understanding of dental resorption.

Keywords:
Internal resorptionpredentinresorptive lesions

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Area of Science:

  • Dentistry
  • Endodontics
  • Oral Pathology

Background:

  • Internal root resorption involves hard tissue loss from the tooth's pulpal surface.
  • This condition damages the organic sheath, predentin, and odontoblastic layer, leading to demineralization.
  • It is less frequently diagnosed than external resorption.

Purpose of the Study:

  • To classify internal resorptive lesions.
  • To distinguish the extent and location of resorption within the tooth.
  • To provide a framework for understanding internal resorption.

Main Methods:

  • Classification of internal resorption based on resorptive site location.
  • Assessment of the extent of tooth tissue involved in resorption.
  • Review of existing classifications for internal inflammatory resorption (transient, persistent).

Main Results:

  • A proposed classification system for internal root resorption.
  • Distinction of lesions based on their specific location within the tooth.
  • Evaluation of the degree of tissue damage and involvement.

Conclusions:

  • A need exists for a comprehensive classification of internal resorptive lesions.
  • This article focuses on classifying internal resorption by location and tissue extent.
  • The proposed classification aids in understanding and diagnosing internal root resorption.