Simultaneous Endocardial and Epicardial Approach for Successful Closure of Left Atrial Appendage With Difficult

Aashish Katapadi1, Rakesh Gopinathannair1, Naga Venkata K Pothineni1

  • 1Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.

JACC. Case Reports
|August 1, 2025
PubMed

Insights

Left atrial appendage closure (LAAC) effectively prevents stroke. Challenging anatomy requires both endocardial and epicardial approaches for successful LAAC outcomes.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Devices

Background:

  • Left atrial appendage closure (LAAC) is a key stroke prevention strategy in atrial fibrillation.
  • Complex left atrial appendage (LAA) anatomy presents significant procedural challenges for LAAC.

Observation:

  • A patient with paroxysmal atrial fibrillation and recurrent falls presented for LAAC.
  • Preoperative imaging revealed challenging LAA anatomy.
  • Initial endocardial LAAC attempts were unsuccessful.

Findings:

  • Epicardial access was obtained, and LAAC was successfully completed using an epicardial device.
  • This case demonstrates the successful application of an epicardial strategy for LAAC in complex anatomy.

Implications:

  • Preprocedural imaging is crucial for identifying challenging LAA anatomy and guiding procedural planning.
  • An upfront epicardial access strategy provides an immediate alternative for LAAC when endocardial approaches fail.
  • Integrating both endocardial and epicardial LAAC techniques is vital for comprehensive stroke prevention programs.
Abstract