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Routes of Drug Administration: Parenteral

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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

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Methods of Teaching Nurses Intravenous Systemic Anticancer Therapy Administration: A Scoping Review.

Michelle O'Dowd¹, Siobhan O'Dowd², Geraldine Austin²

¹School of Nursing, Health Sciences and Disability Studies, ATU St Angela's, Sligo, Ireland; School of Nursing & Midwifery, University of Galway, Ireland.

Seminars in Oncology Nursing

|August 1, 2025

Summary

Nurses require specialized training for safe intravenous systemic anticancer therapy (SACT) administration. This review identifies educational methods and highlights the need for more research, particularly in Europe, to improve patient and provider safety.

Keywords:

Anticancer therapy Chemotherapy IV SACT Intravenous SACT administration Systemic Teaching

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Area of Science:

Oncology Nursing
Healthcare Education
Patient Safety

Background:

Intravenous systemic anticancer therapy (SACT) administration is complex and poses risks of chemotoxic exposure to patients and nurses.
Millions receive IV SACT annually, necessitating robust educational strategies for safe practice.
Identifying gaps in current nursing education for IV SACT is crucial for enhancing safety.

Purpose of the Study:

To conduct a scoping review of published literature on educational methods for teaching nurses the safe administration of IV SACT.
To identify the scope and gaps in the existing body of knowledge regarding IV SACT education for nurses.

Main Methods:

A JBI-guided scoping review was performed, searching multiple databases (CINAHL, Embase, Medline, SCOPUS) and Google Scholar for grey literature.
Studies published between 2010-2023 in English, focusing on teaching methods for safe IV SACT administration, were included.
Data were extracted and presented narratively using the PAGER framework (Patterns, Advances, Gaps, Evidence for Practice, Research Recommendations).

Main Results:

Twenty-two2 full-text articles were reviewed, with 20 studies included for data extraction.
Key patterns identified include diverse education methods (traditional to simulation/VR), interdisciplinary collaboration, global differences in training, and a lack of long-term follow-up.
A significant gap exists in research from Europe, with no European studies included in the review.

Conclusions:

The current literature lacks randomized controlled trials on simulation-based training for IV SACT.
Further interventional research, including meta-analyses and studies on emerging technologies like AI and simulation, is needed.
Enhanced research can bridge the gap between clinical practice and skills training, ultimately improving patient and provider safety in SACT administration.