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Updated: Jan 11, 2026

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Comparing the Efficacy of Peripheral Vessel Cannulation Assistance Utilizing Point Localization and Pathway

Michael D Liddelow1, Ellaby L Hansen1,2, Phuoc Hao Ho1

  • 1VeinTech Pty Ltd, Perth, Western Australia, Australia.

Annals of Biomedical Engineering
|November 10, 2025
PubMed
Summary
This summary is machine-generated.

A novel ultrasound device with pathway visualization significantly improved peripheral intravenous catheter (PIVC) accuracy and success rates in benchtop tests. This technology shows promise for improving cannulation in patients with difficult intravenous access (DIVA).

Keywords:
AnalysisCoronalLocalizationPIVCPathwayTraining

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Area of Science:

  • Medical Devices
  • Ultrasound Technology
  • Vascular Access

Background:

  • First-pass peripheral intravenous catheter (PIVC) insertion failure rates can be as high as 40%, often due to challenges in vein localization.
  • Successful subsequent attempts heavily rely on accurate vein identification, especially in patients with difficult intravenous access (DIVA).

Purpose of the Study:

  • To evaluate a novel ultrasound device featuring coronal pathway visualization for enhancing PIVC insertion accuracy.
  • To compare the efficacy of this device against traditional point localization (single ultrasound frame) in untrained users.

Main Methods:

  • A benchtop study involved 14 untrained investigators performing PIVC insertions into phantom models.
  • Utilized pathway visualization and point localization techniques, collecting data on first-attempt success rates, cannula tip-to-vessel distance, and angle alignment.
  • Investigated user factors like cannulation familiarity and grip technique to inform prototype development.

Main Results:

  • Pathway visualization yielded a higher first-pass success rate (85.7%) compared to point localization (71.4%), effectively halving failure rates.
  • Significantly improved accuracy was observed with pathway visualization regarding cannula tip-to-vessel distance (1.91 mm vs. 4.21 mm, p < .004) and angle alignment (3.49° vs. 12.50°, p < .001).

Conclusions:

  • Coronal pathway visualization significantly enhances PIVC placement accuracy, success rates, and needle-to-vessel alignment compared to point localization.
  • The device holds potential for improving cannulation success in DIVA patients.
  • Further research is needed to compare coronal pathway visualization with traditional transverse visualization (handheld ultrasound).