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Large Peritoneal Macrophages Promote the Resolution of Inflammation in Injured Endometrium

Jingman Li1, Lijie Yin1, Jiali Wang1

  • 1The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.

Inflammation
|August 2, 2025
PubMed
Summary

Large peritoneal macrophages (LPMs) rapidly migrate to injured endometrium, aiding tissue repair by clearing dead cells and reducing inflammation. Their migration is enhanced by 17β-estradiol (E2) levels.

Keywords:
17β-estradiolEndometrial injuryEndometrial repairEndometriumLarge peritoneal macrophages

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