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Updated: Sep 13, 2025

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
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Structural basis of pseudoGTPase-mediated protein-protein interactions

Bing Wang1, Rui Yang1, Chun Wan2

  • 1Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA.

Structure (London, England : 1993)
|August 2, 2025
PubMed
Summary

The assembly chaperone AAGAB contains a pseudoGTPase domain that binds to adaptor complexes, revealing a novel mechanism for regulating membrane trafficking and protein interactions.

Keywords:
AAGABAP1 adaptorAP2 adaptoradaptor complexassembly chaperonemembrane traffickingprotein-protein interactionpseudoGTPasepseudoenzyme

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