Related Experiment Video
Updated: May 13, 2026

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor
Published on: May 2, 2025
The predictive value of platelet parameters and hemorheological indicators for elderly sepsis patients
Xiaoping Li1, Yang He1, Xin Lu1
1Department of Emergency Medicine, First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Gusu District, Soochow, Jiangsu, 215006, PR China.
Abstract:
Sepsis is a life-threatening organ dysfunction. To explore the predictive value of platelet parameters and hemorheological indicators for mortality risk in elderly sepsis patients. The clinical data of 86 elderly patients with sepsis admitted to the intensive care unit of our hospital from June 2020 to June 2023 were retrospectively analyzed. According to the survival outcome, the patients were divided into the death group (28 cases) and the survival group (58 cases). The platelet parameters and hemorheological indicators of the two groups were compared. Pearson correlation analysis was used to analyze platelet parameters, hemorheology and Sequential Organ Failure Assessment (SOFA). Patients in the death group had higher APACHE II score, SOFA score, MPV, plasma viscosity, Equation K Value of ESR, and RDW than those in the survival group (P < 0.05). SOFA score was positively correlated with MPV, plasma viscosity, Equation K Value of ESR and RDW (P < 0.05), but not correlated with PLT and PDW (P < 0.05). APACHE II score, SOFA score, MPV, plasma viscosity, Equation K Value of ESR, and RDW were risk factors for mortality in elderly sepsis patients (P < 0.05). The joint prediction had higher performance than individual indicator (all P < 0.05). MPV, plasma viscosity, equation K value of ESR, and RDW were related to multiple organ failure in elderly sepsis patients, and could be used to predict the risk of death in patients, with good predictive performance.
Related Concept Videos
Pre-Procedural Guidelines for Assessing Blood Pressure
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...

