Metabolic evaluation in paediatric urolithiasis: Is a key component being overlooked? An international survey by the

Y Quiroz Madarriaga1, M I Dönmez2, R J M Lammers3

  • 1Unidad de Urología Pediátrica, Fundación Puigvert, Barcelona, Spain.

PubMed

Insights

Paediatric urolithiasis is rising globally. Metabolic evaluations for pediatric kidney stones are inconsistent, with limited urologist involvement and a need for standardized guidelines and education.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Metabolic Disorders

Background:

  • Paediatric urolithiasis incidence is increasing worldwide.
  • Metabolic abnormalities are a significant factor in pediatric kidney stone formation.
  • Standardized protocols for metabolic evaluation in children with urolithiasis are currently lacking.

Purpose of the Study:

  • To assess current practices and knowledge regarding metabolic evaluation of paediatric urolithiasis among pediatric urologists globally.
  • To identify gaps in current diagnostic and treatment strategies for pediatric kidney stone disease.

Main Methods:

  • An international survey was conducted among pediatric urologists.
  • Data collected included clinician demographics and metabolic evaluation strategies for pediatric stone disease.
  • Responses were gathered from 194 clinicians across 49 countries.

Main Results:

  • Only 11% of clinicians routinely performed metabolic evaluations for pediatric urolithiasis.
  • While 78% requested stone analysis, only 46% ordered 24-hour urine studies.
  • Paediatric nephrologists managed evaluations in 84% of cases, with limited urologist involvement (<25%).
  • Knowledge of spot urine indices and crystalluria as a risk factor was varied (55% recognized crystalluria).
  • Fewer than one-third of urologists felt confident interpreting results or initiating treatment.

Conclusions:

  • Significant inconsistencies exist in the metabolic evaluation of paediatric urolithiasis.
  • There is a need for clearer guidelines and enhanced education for pediatric urologists.
  • Increased urologist involvement is crucial for improving metabolic assessment and management of pediatric kidney stones.

Related Concept Videos

Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
23
Urinary Tract Calculi I: Introduction01:28

Urinary Tract Calculi I: Introduction

Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
44
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
40
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
27
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
32
Urinary Tract Calculi V: Nursing Management01:28

Urinary Tract Calculi V: Nursing Management

AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
28