Related Experiment Video
Updated: Sep 13, 2025
11:19
Ex vivo Live Imaging of Lung Metastasis and Their Microenvironment
Published on: February 3, 2016
12.6K
In vivo exosome imaging: applications of diverse visualization techniques.
Seongje Hong1, Hyun Chul Jo1, Hye-Lin Kim2
1Department of Anatomy, College of Medicine, Chung-Ang University, Seoul 06974, Korea.
BMB Reports
|August 4, 2025
Summary
This review explores in vivo exosome imaging techniques for tracking exosomes, which are vital for intercellular communication and potential therapeutics. Advances in visualization methods are crucial for advancing exosome-based diagnostics and precision medicine.
Area of Science:
- Biomedical imaging
- Nanotechnology
- Cell biology
Background:
- Exosomes are nanoscale vesicles crucial for intercellular communication, carrying proteins, nucleic acids, and lipids.
- Their biocompatibility and targeting ability make exosomes promising for diagnostics and therapeutics in diseases like cancer and neurodegenerative disorders.
- Monitoring exosome biodistribution in vivo is essential for their clinical application.
Conclusions:
- Emerging multimodal platforms and labeling innovations hold potential to overcome current imaging limitations.
- Development of non-invasive, sensitive, and clinically translatable imaging systems is needed.
- Advances in exosome imaging are key to realizing the diagnostic and therapeutic potential of exosomes in precision medicine.
