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Heart Failure II: Pathophysiology

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...

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Related Experiment Video

Updated: Sep 13, 2025

Assessing Cardiomyocyte Subtypes Following Transcription Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts

Assessing Cardiomyocyte Subtypes Following Transcription Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts

Published on: March 22, 2017

Embryonic transcripts in heart failure: Time for reprogrammed thinking?

Thorsten Kessler^1,2, Michael Winkler^1,2, Antoni Bayes-Genis^3,4

¹Department of Cardiovascular Diseases, German Heart Center, TUM University Hospital, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.

European Journal of Heart Failure

|August 4, 2025

Summary

No abstract available in PubMed .

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