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Atypical Spitz Tumor Mimicking Pyogenic Granuloma: A Case Report and Literature Review
Yuka Nagasaka1, Tomohiro Shiraishi1, Takahiro Shibayama2
1Department of Plastic and Reconstructive Surgery, Kyorin University School of Medicine, Tokyo, Japan.
Journal of Plastic and Reconstructive Surgery
|August 4, 2025
Summary
Atypical Spitz tumors, a type of Spitzoid melanocytic lesion, present diagnostic challenges in children. This case highlights the importance of considering these tumors in pediatric skin lesion evaluations.
Area of Science:
- Dermatology
- Pediatric Oncology
- Pathology
Background:
- Atypical Spitz tumors are a subset of Spitzoid melanocytic lesions.
- These lesions exhibit atypical features and indeterminate biological potential.
- Accurate diagnosis of atypical Spitz tumors is challenging clinically and pathologically.
Observation:
- A 1-year-old Japanese girl presented with a rapidly growing skin lesion.
- The lesion clinically resembled a pyogenic granuloma.
- The patient was diagnosed with an atypical Spitz tumor.
Findings:
- Atypical Spitz tumors require careful consideration in pediatric differential diagnoses.
- The case underscores the diagnostic complexity associated with these lesions.
- Rapidly enlarging pediatric skin lesions can represent atypical Spitz tumors.
Implications:
- Timely and accurate diagnosis of atypical Spitz tumors is crucial for pediatric patients.
- Integrating atypical Spitz tumors into the differential diagnosis of pediatric neoplasms improves patient care.
- Understanding the clinical presentation and diagnostic challenges aids in managing pediatric skin tumors.

