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A Case Report of High-Dose Repetitive Transcranial Magnetic Stimulation-Induced Excessive Laughing in a 6-Year-Old
Junzi Long1,2,3, Xingxing Liao1,2,3, Kaiyue Han1,2
1School of Rehabilitation Capital Medical University Beijing China.
Clinical Case Reports
|August 4, 2025
Abstract:
High-dose transcranial magnetic stimulation-induced excessive laughter in a 6-year-old autistic male. We hypothesized that this phenomenon reflected prefrontal disinhibition or exaggerated emotional response. This case emphasizes the necessity for modified treatment protocols with concurrent psychiatric assessment, emotional evaluation, and neurophysiological monitoring when encountering such adverse effects during neuromodulation therapy.

