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Updated: Jul 23, 2026

Virtual Reality Experiments with Physiological Measures
Published on: August 29, 2018
Virtual Reality as a Tool for Wellbeing in Public Healthcare: Analysis of a Clinical Case
Fabiana Nuccetelli1, Valeria Gabellone1, Pier Luigi Lopalco1
1Department of Experimental Medicine, University of Salento, Lecce, Italy.
Background:
Virtual Reality (VR) is a technology that enables the creation of immersive, interactive, and collaborative environments, with extensive applications in the realm of e-Health.
Methods:
This study aimed to reduce stress and anxiety in hospitalised patients by employing guided virtual scenarios and non-invasive biosensors.
Results:
During the initial experimental phase, conducted on 33 patients in a cardiac rehabilitation ward, improvements were observed in stress levels (-11.3%), depression (-4.2%), and anxiety (-3.2%). Supporting these results, a specific clinical case analysis revealed significant improvements in an 82-year-old woman with moderate depression and severe social isolation. Following the VR intervention, the patient experienced a substantial reduction in isolation, heightened motivation for daily activities, and enhanced social interaction quality, with a 35% increase in perceived quality of life. Physiological improvements included reduced sympathetic nervous system arousal and greater heart rate variability stability.
Conclusions:
These findings underscore VR's potential to promote psychophysical wellbeing and improve healthcare service quality, advocating innovative preventive and therapeutic methods.
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