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Updated: Sep 12, 2025

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
[Scoping review on the identification and evaluation of available digital applications for bipolar disorder]
Taha Johanna Henning1, Orestis Rakitzis1, Jakob Kaminski1,2
1Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Klinik für Psychiatrie und Psychotherapie, Charitéplatz 1, 10117, Berlin, Deutschland.
Background:
Bipolar disorders require long-term monitoring. Digital applications, such as smartphone apps, offer potential for self-management and early detection but there are uncertainties regarding availability, guideline conformity and evidence. In Germany, specific digital health applications (DiGAs) for bipolar disorders are lacking, highlighting regulatory and healthcare delivery challenges.
Aim:
This review examines apps for bipolar disorder available in Germany with respect to their functions, availability and evidence base.
Material And Methods:
Between January and March 2025 a systematic search was conducted in the databases MindApps.org and MindTools.io for apps. Functions, research evidence, languages, cost models, and app-store availability were recorded. Additionally, scientific studies on the identified apps were reviewed.
Results:
A total of 18 apps were identified 11 of which are specifically for bipolar disorders. The functions range from mood and symptom tracking to psychoeducational contents. Of the apps six had published studies but none showed significant improvements in symptoms.
Discussion:
Although digital interventions show promise for improving the treatment of bipolar disorder, large-scale, methodologically rigorous randomized controlled trials with standardized endpoints are still lacking. In Germany no DiGAs specifically designed for this patient group are currently available. Moreover, for sustainable integration into routine care of a chronic condition such as bipolar disorder, dependable reimbursement models and comprehensive long-term studies are also required.
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