Coronary artery spasm complicated by atrial septal puncture: A case report

Ping Gong1, Yong Da Zhang, Yuan Zhi Zhou

  • 1Mianyang 404 Hospital, Mianyang, China.

Medicine
|August 5, 2025
PubMed

Insights

Severe coronary artery spasm during atrial septal puncture can cause ST-segment elevation on ECG in atrial fibrillation patients. Prompt intervention with percutaneous coronary intervention and stenting is crucial for managing this rare complication.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Electrophysiology

Background:

  • ST-segment elevation on electrocardiogram (ECG) during transseptal puncture for atrial fibrillation is uncommon.
  • The exact cause of this ECG change remains unclear.

Purpose of the Study:

  • To identify the cause of ST-segment elevation during transseptal puncture.
  • To report a case of severe coronary artery spasm as a cause of ST-segment elevation.

Main Methods:

  • A 66-year-old woman with atrial fibrillation underwent transseptal puncture.
  • She developed ST-segment elevation and hypotension post-procedure.
  • Coronary angiography revealed right coronary artery occlusion and spasm, treated with percutaneous coronary intervention and stenting.

Main Results:

  • The patient experienced ST-segment elevation and hemodynamic instability after atrial septal puncture.
  • Percutaneous coronary intervention successfully treated the coronary artery spasm and stenosis.
  • The patient recovered and was discharged after 12 days.

Conclusions:

  • Severe coronary artery spasm can cause ST-segment elevation during atrial septal puncture.
  • Concurrent coronary artery stenosis may lead to persistent vasospasm and severe complications.
  • Preoperative coronary angiography or CTA is recommended to identify patients at risk.
Abstract

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