Related Experiment Video
Updated: Sep 12, 2025

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
Published on: December 1, 2023
The short term impact of uncomplicated cataract surgery on retinal layers thickness
Marco Gioia1, Maddalena De Bernardo1, Aniello La Marca1
1Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi, Italy.
Objective Or Purpose:
To detect the short-term impact of cataract surgery on retinal layers thickness, as the exact mechanism of fundus changes after phacoemulsification has not yet been fully clarified.
Design:
A retrospective observational study.
Subjects Participants And/Or Controls:
Seventy eyes of 70 patients with age ranging from 49 to 92 years, scheduled for cataract surgery, were included.
Methods Intervention Or Testing:
All subjects underwent a complete ophthalmological examination, including ART-OCT volume with Heidelberg Spectralis before and approximately one month later cataract surgery.
Main Outcome Measures:
The macula was divided into a central foveal region and four parafoveal regions (superior, inferior, nasal, temporal). The scans were then automatically segmented into the different retinal layers and the changes in each layer were assessed.
Results:
The results revealed that both the inner retinal layers and the entire retina exhibited a statistically significant thickening in foveal and parafoveal region: IRL (p < 0.001), ONL (p < 0.001), GCL (p = 0.010), RNFL (p = 0.020), and ALL (p < 0.001). Conversely, the outer retinal layers showed a statistically significant reduction in thickness only within the parafoveal regions: ORL (p < 0.001).
Conclusion:
This study may provide a pathophysiological explanation for post-phacoemulsification changes affecting the retina.
More Related Videos
04:59Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
Published on: July 7, 2023
10:10Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022