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Related Concept Videos

Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

354
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
354
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

191
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
191
Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

331
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
331
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

207
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
207
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

201
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
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Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

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Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
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Updated: Sep 12, 2025

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Gastric Cancer Endoscopic Screening in an Intermediate-Risk Country-A Dual-Center Pilot Program.

M B Mourato1,2, N Pratas2, A Branco Pereira2

  • 1NOVA National School of Public Health, Public Health Research Centre, Comprehensive Health Research Center, CHRC, LA-REAL, CCAL, NOVA University Lisbon, Lisbon, Portugal.

Helicobacter
|August 5, 2025
PubMed
Summary
This summary is machine-generated.

Opportunistic upper endoscopy integrated with colorectal cancer screening is feasible and diagnostically valuable in Portugal. This approach effectively identifies precancerous conditions and malignancies, supporting structured screening strategies.

Keywords:
Helicobacter pyloriearly detection of cancergastrointestinal endoscopygastrointestinal neoplasmsmass screeningprecancerous conditionspublic healthstomach neoplasms

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Area of Science:

  • Gastroenterology
  • Oncology
  • Public Health

Background:

  • Gastric cancer is a global health concern, often diagnosed late in Western countries.
  • Portugal lacks a national gastric cancer screening program despite evidence for its benefit in intermediate-risk areas.
  • This study investigates opportunistic upper endoscopy alongside colorectal cancer screening.

Purpose of the Study:

  • To assess the feasibility and adherence of opportunistic upper endoscopy.
  • To evaluate the diagnostic yield of upper endoscopy when integrated with colorectal cancer screening.
  • To provide evidence for implementing structured screening strategies in Portugal.

Main Methods:

  • An observational retrospective study was conducted in two Portuguese endoscopy units.
  • Individuals aged 50-74 years scheduled for screening colonoscopy were invited for upper endoscopy.
  • Data on demographics, endoscopic findings, and histology were collected and analyzed.

Main Results:

  • High acceptance rate (94.8%) for upper endoscopy among invited individuals.
  • Prevalence of Helicobacter pylori infection (30.8%), chronic atrophic gastritis (36.9%), and intestinal metaplasia (10.1%).
  • Detected neoplastic lesions included 1.9% malignancy rate (gastric adenocarcinoma, GISTs) and 0.5% low-grade intraepithelial neoplasia; 29.2% precancerous and 3.4% invasive colorectal cancer lesions were found.

Conclusions:

  • Opportunistic upper endoscopy integrated with colorectal cancer screening is feasible and well-accepted in an intermediate-risk Western population.
  • The high detection rate of precancerous conditions and malignancies underscores the need for structured screening programs.
  • Findings support broader implementation of integrated screening strategies in similar healthcare settings.