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Remimazolam for anesthesia and sedation in pediatric ambulatory surgery: A scoping review protocol

Yi Zhang1, Linyun Wang2, Shuang Guo1

  • 1Department of Anesthesiology, Maternal and Child Health Hospital of Wanzhou District, Chongqing City, People's Republic of China.

Plos One
|August 5, 2025
PubMed

Insights

This scoping review maps evidence on remimazolam for pediatric ambulatory surgery anesthesia. It identifies current applications, characteristics, and knowledge gaps for this rapid-acting sedative.

Area of Science:

  • Anesthesiology
  • Pharmacology

Background:

  • Remimazolam is a novel benzodiazepine with potential for pediatric anesthesia and sedation.
  • Its rapid onset, predictable metabolism, and safety profile are advantageous for outpatient procedures.
  • Limited pediatric evidence exists despite growing adult research.

Purpose of the Study:

  • To systematically review and map existing evidence on remimazolam's use in pediatric ambulatory surgery.
  • Identify key concepts, evidence sources, and knowledge gaps regarding its application and features.

Main Methods:

  • Adherence to JBI methodology and PRISMA-ScR guidelines.
  • Comprehensive search across multiple international and Chinese databases.
  • Inclusion of all studies on remimazolam in patients ≤18 years for ambulatory surgery.
  • Independent data screening and extraction by two reviewers.

Main Results:

  • (Results will be populated upon study completion)

Conclusions:

  • (Conclusions will be populated upon study completion)
Abstract

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