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Validation of the Telephone Version of S3-Non-Invasive Ventilation Questionnaire in Patients with Chronic Obstructive
Leonor Roseta1, Pedro Viegas2, Maria João Oliveira2
1Pulmonology Department, Unidade Local de Saúde de Gaia/Espinho, Porto, Portugal, leonor.roseta@gmail.com.
Introduction:
This study aimed to validate the telephone administration of the S3-non-invasive ventilation questionnaire (S3-NIV), a patient-reported outcome measure assessing the impact of NIV on patients' quality of life, in a Portuguese cohort of patients with chronic obstructive pulmonary disease (COPD) and chronic respiratory failure (CRF) under NIV.
Methods:
We conducted a prospective observational study with patients with COPD and CRF at a Portuguese tertiary hospital, including participants who completed both paper and telephone versions of the S3-NIV in randomized order within 10 days.
Results:
Internal consistency was good in both telephone and paper versions: S3-NIV-total (α = 0.78 and 0.74), S3-NIV-respiratory symptoms (α = 0.78 and 0.74), and S3-NIV-sleep and side effects (α = 0.68 and 0.62). Moderate to strong convergent validity was found (S3-NIV-total - rs = 0.75, S3-NIV-respiratory symptoms - rs = 0.73, S3-NIV-sleep and side effects - rs = 0.67). Relative reliability was good in all scores: S3-NIV-total (ICC 0.74 [95% CI 0.61; 0.83]), S3-NIV-respiratory symptoms (ICC 0.74 [95% CI 0.61; 0.83]), and S3-NIV-sleep and side effects (ICC 0.65 [95% CI 0.50; 0.77]). Bland-Altman plots demonstrated reasonable agreement, with most differences within acceptable limits and a minor bias.
Conclusion:
The telephone-administered S3-NIV is a valid, reliable tool for assessing the impact of NIV on quality of life in patients with COPD, supporting its use in remote clinical settings.
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