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First Clinical Experiences with Microfocused Ultrasound in Infraorbital Rejuvenation: A Clinically and Scientifically
Wolfram Heitzmann1, Jennifer Lynn Schiefer1, Laura Lanckohr1
1Department of Plastic Surgery, Hand Surgery, Burn Center, Cologne-Merheim Medical Center (CMMC), University of Witten, Herdecke, Germany.
Objectives & Hypotheses:
The infraorbital region is challenging to treat due to complex anatomy and issues like skin laxity, malar edema, and malar mounds. This study evaluates micro focused ultrasound with visualization (MFU-V) as a non-invasive treatment for infraorbital rejuvenation, hypothesizing improved skin tightening and contouring.
Study Design:
A case series with anatomical analysis and literature review.
Methods:
Five female patients (aged 42-54) with mild-to-moderate skin laxity underwent MFU-V treatment using 1.5, 3.0, and 4.5 mm transducers. Standardized photos and assessment scales (Merz Infraorbital Hollow Scale, GAIS) were used at baseline and 6 months.
Results:
MFU-V led to visible improvements in periorbital skin tightening and reduction of malar mounds, especially in more pronounced cases. No adverse effects occurred.
Conclusion:
MFU-V is a safe, effective, and non-invasive option for periorbital rejuvenation. It may serve as an alternative to surgical treatment for infraorbital skin laxity and malar deformities. Larger studies are needed to confirm efficacy.

