Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Disorders of the Male Reproductive System

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Enhancing pedicle screw placement training with a visual tracking guide template in augmented reality navigation.

Frontiers in medicine·2026

Same author

Real-time augmented reality navigation in brain glioma resection: a pilot feasibility study.

Frontiers in surgery·2026

Same author

Efficacy and Safety of En-Bloc Laser Enucleation of the Prostate for Benign Prostatic Obstruction: An Evidence-Based Analysis of Clinical Studies.

Journal of investigative surgery : the official journal of the Academy of Surgical Research·2026

Same author

The rising burden of male genitourinary cancers in middle- and high-income countries.

Frontiers in oncology·2026

Same author

Spatial analysis of predictors of prostate cancer incidence in the united states using multiscale geographically weighted regression (MGWR).

BMC public health·2026

Same author

Micro/nanoplastic-induced alterations in cellular fate and full-cycle spermatogenesis: A mechanistic review and perspective on intergenerational risks.

Environmental pollution (Barking, Essex : 1987)·2026

Search research articles

Related Experiment Video

Updated: Apr 30, 2026

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI

Published on: November 27, 2019

Altered gray matter morphometry in psychogenic erectile dysfunction patients: A Surface-based morphometry study.

Zilei Tian^1,2,3, Ziyang Ma⁴, Beihong Dou⁵

¹Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, Sichuan, China.

Scientific Reports

|August 6, 2025

Summary

This summary is machine-generated.

Psychogenic erectile dysfunction (pED) shows distinct cortical morphological changes in brain regions like the orbitofrontal cortex. These brain alterations correlate with symptoms and can help differentiate pED patients from healthy individuals.

Keywords:

Brain cortical thickness, cortical complexity Erectile dysfunction MRI Machine learning Reward system

More Related Videos

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

Published on: February 4, 2022

Related Experiment Videos

Last Updated: Apr 30, 2026

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI

Published on: November 27, 2019

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

Published on: February 4, 2022

Area of Science:

Neuroscience
Psychiatry
Medical Imaging

Background:

Psychogenic erectile dysfunction (pED) is a common condition without a clear organic cause.
Understanding the brain's role in pED is crucial for diagnosis and treatment.
Cortical morphological characteristics in pED patients have not been well-studied.

Purpose of the Study:

To investigate cortical morphological alterations in pED patients using surface-based morphometry (SBM).
To explore the correlation between these morphological changes and clinical symptoms.
To assess the feasibility of using these features for objective pED diagnosis.

Main Methods:

Enrolled 50 pED patients and 50 healthy controls (HC).
Utilized surface-based morphometry (SBM) to analyze cortical thickness, sulcus depth, gyrification index, and fractal dimension.
Performed correlation analysis and developed a support vector classification model.

Main Results:

pED patients exhibited significant cortical morphological alterations in the orbitofrontal cortex, cingulate cortex, dorsolateral prefrontal cortex, and precentral gyrus.
These alterations were correlated with pED clinical symptoms.
A classifier based on 11 features achieved 82% accuracy in distinguishing pED from HC.

Conclusions:

pED is associated with specific cortical morphological aberrations.
These findings enhance understanding of pED's central pathological patterns.
The study supports objective diagnosis and potential neuromodulation strategies for pED.