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IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Intracochlear Imaging Using IVUS and OFDI: A Cadaveric Feasibility Study.

Ayu Akazawa1, Takeshi Fujita1, Jun Yokoi1

  • 1Department of Otolaryngology-Head and Neck Surgery Kobe University Hospital Kobe Japan.

Laryngoscope Investigative Otolaryngology
|August 6, 2025
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Summary

Optical frequency domain imaging (OFDI) and intravascular ultrasound (IVUS) are feasible for intracochlear imaging. OFDI offers superior resolution, while IVUS provides greater penetration for assessing cochlear structures and pathologies.

Keywords:
cochlear imagingcochlear implant surgeryintravascular ultrasound (IVUS)optical coherence tomography (OCT)optical frequency domain imaging (OFDI)

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Area of Science:

  • Otoacoustic emissions and inner ear imaging
  • Medical imaging techniques in otology
  • Intracochlear visualization technologies

Background:

  • Accurate visualization of intracochlear structures is crucial for diagnosing hearing loss and guiding surgical interventions.
  • Current imaging modalities have limitations in resolution and penetration depth within the cochlea.
  • Developing advanced imaging techniques is essential for improving otologic surgical outcomes.

Purpose of the Study:

  • To evaluate the feasibility of optical frequency domain imaging (OFDI) and intravascular ultrasound (IVUS) for intracochlear imaging in human cadaveric specimens.
  • To compare the resolution, depth penetration, and diagnostic capabilities of OFDI and IVUS for identifying cochlear anatomy and pathology.
  • To assess the potential of these techniques for intraoperative monitoring during cochlear implant surgery.

Main Methods:

  • Human cadaveric temporal bones were utilized for intracochlear imaging.
  • OFDI and IVUS probes were inserted into the scala tympani via the round window.
  • Imaging data were acquired using specific OFDI and IVUS systems and compared with histological findings.

Main Results:

  • OFDI provided high-resolution imaging of the basal turn, clearly visualizing the basilar membrane, Reissner's membrane, scala media, and organ of Corti.
  • IVUS demonstrated lower resolution but greater tissue penetration compared to OFDI.
  • Both techniques successfully identified basilar membrane disruptions, a potential complication in cochlear implant surgery.

Conclusions:

  • OFDI and IVUS are feasible for intracochlear imaging, offering complementary strengths in resolution and penetration.
  • This study marks the first application of IVUS for intracochlear imaging, highlighting its potential for intraoperative guidance and pathology assessment.
  • These advanced imaging modalities hold promise for enhancing the diagnosis and surgical management of inner ear conditions.