Related Experiment Video
Updated: Sep 12, 2025

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
Published on: April 17, 2020
Neoadjuvant Treatment and Postoperative Complications After Surgery for Esophageal Cancer: A Population-Based,
Ville E J Sirviö1, Jari V Räsänen2, Olli Helminen3
1Department of Oesophageal and General Thoracic Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. ville.ej.sirvio@helsinki.fi.
Background:
The role of neoadjuvant treatment and its modalities in the risk of complications after esophagectomy in national practice is unclear. The aim of this study was to compare postoperative complications after neoadjuvant treatment (nT) and upfront surgery (US), neoadjuvant chemoradiotherapy (nCRT) and neoadjuvant chemotherapy (nCT), and to assess the effect of complications from neoadjuvant treatment in surgical risk.
Patients And Methods:
All patients undergoing esophagectomy for esophageal cancer in Finland in 2005-2016 were included. Incidences of all postoperative complications defined by the Esophagectomy Complications Consensus Group as well as major complications, 90-day mortality, and hospital and ICU stay were reported stratified by treatment strategy (nT versus US, nCRT versus nCT, nT-complication versus no complication). Primary outcomes were compared using logistic regression in these patient groups.
Results:
Out of 774 patients, 423 (55%) had nT and 351 (45%) had US. Of the 423 patients undergoing nT, 249 (59%) had nCT, 3 (1%) had radiotherapy only, and 171 (40%) had nCRT. After adjusting for relevant confounders, there were no increases in pneumonia, anastomotic leak, major complications, overall complications, or 90-day mortality with nT compared with US, nCRT compared with nCT, or in patients with nT complications compared with those without.
Conclusions:
This nationwide, population-based study reports no difference in postoperative complications or mortality after nT compared with US or nCRT compared with nCT. Patients with neoadjuvant treatment complications were not at higher risk of postoperative complications.
More Related Videos
09:04Low-Cost Single-Port LoCoSP Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy
Published on: September 11, 2021
03:32Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
Published on: December 27, 2024
Related Concept Videos
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Varices-I: Introduction