Case report: psychosis with Stevens-Johnson syndrome and toxic epidermal necrolysis

A case is presented of a 36-year-old woman who developed a psychosis following an apparent systemic allergic reaction to phenytoin and/or phenobarbital. She was initially diagnosed as having Stevens-Johnson syndrome and toxic epidermal necrolysis with the subsequent development of a psychosis. The authors were able to demonstrate a previously undiagnosed neurological impairment that they feel may be related to both the drug reaction and the psychosis.