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Updated: Sep 12, 2025

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
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Polymerization and replication of primordial RNA induced by clay-water interface dynamics

Carla Alejandre1,2, Adrián Aguirre-Tamaral1,3, Carlos Briones1

  • 1Centro de Astrobiología (CAB), CSIC-INTA, Torrejón de Ardoz, Madrid, Spain.

Communications Chemistry
|August 7, 2025
PubMed
Summary

Early Earth conditions, including tidal oscillations and clay mineral interfaces, facilitated RNA polymerization and replication. A four-letter genetic alphabet offers optimal speed and diversity for life

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