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Updated: Sep 12, 2025

Author Spotlight: Advancements in Nanoparticle Technology for Drug Delivery and Immunotherapy
Published on: November 10, 2023
Nanotechnology for immuno-oncology
Adam J Grippin1, DaeYong Lee2,3, Eileen E Parkes4
1Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
None:
Although the first generation of cancer immunotherapeutics produced unprecedented improvements in clinical outcomes for individuals with cancer, novel strategies to increase treatment specificity, delivery efficiency and pharmacokinetics are still needed. In this Review, we describe the potential advantages and current limitations of nanomaterials for cancer immunotherapy and highlight rational uses of nanosystems to generate potent and durable antitumor immune responses. We close with a review of the current state of clinical development of nanomedicine for cancer immunotherapy.
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