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Related Experiment Video

Updated: Sep 12, 2025

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
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Technique to Reduce Wound Size: The Double-Opposing Purse-String and Horizontal Continuous Closure Algorithm.

Alexander L Mostovych1, Lexina R Patel1, Kartik Garg2

  • 1University of Louisville School of Medicine, Louisville, Kentucky.

Eplasty
|August 8, 2025
PubMed
Summary
This summary is machine-generated.

A simplified double-opposing purse-string suture (PSS) technique effectively reduces complex wound size, minimizing or eliminating the need for skin grafts. This low-risk method benefits patients with comorbidities, improving surgical reconstruction outcomes.

Keywords:
Complex Wound ClosurePurse-StringSkin CancerSkin GraftingSurgical TechniqueWound Reconstruction

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Area of Science:

  • Plastic Surgery
  • Wound Healing
  • Surgical Techniques

Background:

  • Complex wound reconstruction requires careful planning for optimal outcomes.
  • Conservative approaches are preferred for high-risk patients with comorbidities.
  • A simplified, low-risk double-opposing purse-string suture (PSS) technique offers an alternative to complex reconstruction methods.

Purpose of the Study:

  • To evaluate the efficacy of the double-opposing purse-string suture (PSS) and horizontal continuous closure technique in complex wound reconstruction.
  • To assess the technique's impact on reducing wound size and the need for skin grafts, especially in patients with comorbidities.

Main Methods:

  • Retrospective chart review of 57 wounds in 46 patients undergoing reconstruction with the double-opposing PSS technique.
  • Analysis of defect size before and after closure using a 2-tailed paired t test.
  • Evaluation of skin graft requirements and donor site sizes.

Main Results:

  • The double-opposing PSS technique significantly reduced average defect size from 61 cm² to 12 cm² (P = .0003).
  • 63% of wounds (21 out of 57) were successfully closed without skin grafts.
  • Wounds requiring skin grafts had smaller graft and donor sites.

Conclusions:

  • The double-opposing PSS technique is effective for complex wound closure, particularly in patients with comorbidities.
  • This method simplifies reconstruction, reduces wound size, and minimizes the need for or size of skin grafts.
  • The technique lowers the risk of complications by simplifying wound management and reducing overall wound dimensions.