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Surface charge on polymeric implants and calcified tissues: interfacial implications.

S I Stupp, R Kusleika

    Journal of Biomedical Materials Research
    |March 1, 1985
    PubMed
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    Human bone, dentin, and enamel exhibit natural electrical polarization. This surface charge, linked to collagen denaturation or mineral phase interactions, significantly enhances dentin/acrylic polymer joint strength through electrostatic coupling.

    Area of Science:

    • Biomaterials Science
    • Biophysics
    • Dental Materials

    Background:

    • Human bone, dentin, and enamel possess inherent surface charges.
    • Understanding these charges is crucial for biomaterial interface optimization.
    • Previous research has not fully elucidated the origin and implications of these surface charges.

    Purpose of the Study:

    • To investigate the origin and characteristics of surface polarization in human bone, dentin, and enamel.
    • To explore the relationship between tissue surface charge and adhesive joint strength.
    • To hypothesize the mechanism of enhanced adhesion through electrostatic coupling.

    Main Methods:

    • Analysis of human bone, dentin, and enamel using Thermally Stimulated Discharge (TSD) current measurements.

    Related Experiment Videos

  • Calculation of activation energies and thermal ranges for TSD currents.
  • Measurement of adhesive strength in dentin/acrylic polymer joints with and without externally charged adhesive particles.

    • Main Results:

    • Freshly extracted human tissues exhibited spontaneous TSD current maxima without external electrical stimulation.
    • Collagen denaturation is implicated in the loss/appearance of net surface charge on bone and dentin.
    • Enamel TSD maxima suggest dipolar alignment by surface charges in the mineral phase.
    • Adhesive joint strength in dentin/acrylic polymer increased twofold or more with externally charged adhesive particles.

    Conclusions:

    • The study demonstrates intrinsic surface polarization in dental and bone tissues.
    • Surface charge plays a significant role in the mechanical properties of tissue-biomaterial interfaces.
    • Electrostatic coupling between tissue polarization domains and setting biomaterials is a viable mechanism for improving adhesive strength and interfacial integrity.