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Updated: Sep 12, 2025
Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Platelet-to-Haemoglobin Ratio Predicts the Development of Left Ventricular Apical Thrombus
Engin Algül1, Nail Burak Özbeyaz2, Haluk Furkan Şahan1
1Etlik City Hospital, Department of Cardiology, Ankara, Turkey.
Objective:
Apical thrombus (AT) is a severe complication in myocardial infarction (MI), increasing the risk of thromboembolic events. Platelet-to-haemoglobin ratio (PHR) is a novel, inexpensive predictor of cardiovascular outcomes. This study explores the association between PHR and AT in MI patients.
Materials & Methods:
This retrospective study included 690 anterior MI patients (314 patients with AT and 376 patients without AT as a control group). Blood samples were analysed to calculate PHR, and echocardiographic evaluations identified AT. Logistic regression and ROC analysis determined independent predictors and the optimal PHR cut-off value for AT.
Results:
PHRwas significantly higher in the AT group (2.03 ± 0.64 vs. 1.85 ± 0.50; p <0.001).Multivariate analysis identified PHR, proximal LAD lesions, and lower LVEF as independent predictors. The PHR cut-off of 1.88 showed 69.3% sensitivity and 68.4% specificity.
Conclusion:
PHR is a simple, accessible marker for predicting AT in MI patients. Its use may improve early risk stratification and clinical outcomes.
