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Updated: Sep 12, 2025

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Pectus Excavatum, Patent Foramen Ovale, and Migraine in the Same Patient
Jeremy Tricard1, François Maltais2, Josep Rodès-Cabau3
1Cardiothoracic Surgery Department, Dupuytren Hospital, Limoges, France.
Background:
A patent foramen ovale (PFO) can be found in patients with pectus excavatum (PE); PFO can be associated with migraines.
Case Summary:
A 22-year-old woman presents a PE and a history of recurrent migraines. Pulsed oxygen saturation at effort decreased from 97% to 92%. A transthoracic echocardiography showed a PFO. Five years after the Ravitch procedure, pulsed oxygen saturation remained stable at effort, no PFO was shown on transthoracic echocardiography, and migraine disappeared.
Discussion:
Our observation is the first description of the PE, PFO, and migraine association. The correction of PE has allowed the closure of the PFO and improved migraines.
Take-Home Messages:
This case report suggests that a patient presenting a PE should undergo a comprehensive cardiorespiratory evaluation. Similarly, patients with a symptomatic PFO and PE should benefit from a multidisciplinary discussion involving thoracic surgeons to determine the best approach to treat the PFO.
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