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Implementation Determinants of HIV Testing and Pre-Exposure Prophylaxis in Community Pharmacies in Philadelphia, PA
Cedric H Bien-Gund1,2,3, Anna Sweeney4, Brandon Ptak5
1Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
AIDS Patient Care and Stds
|August 8, 2025
Summary
Community pharmacies can improve HIV testing and pre-exposure prophylaxis (PrEP) access. However, legal barriers and workflow integration challenges hinder successful implementation, requiring targeted strategies for sustainability.
Area of Science:
- Public Health
- Implementation Science
- Pharmacy Practice
Background:
- Community pharmacies are vital for expanding access to HIV testing and pre-exposure prophylaxis (PrEP).
- Few US pharmacies have successfully integrated these HIV prevention services.
- Philadelphia, an Ending the HIV Epidemic priority jurisdiction, faces challenges due to restrictive state laws.
Purpose of the Study:
- To investigate implementation barriers and facilitators for pharmacy-based HIV testing and PrEP initiation.
- To identify strategies for overcoming challenges in a state with restrictive pharmacy practice laws.
Main Methods:
- Sequential, exploratory mixed-methods study design.
- 15 in-depth interviews with pharmacists and partners.
- Online survey of 59 pharmacists, students, and technicians.
- Analysis using the Consolidated Framework for Implementation Research.
Main Results:
- HIV testing initiated at three sites, but no sites implemented PrEP.
- Barriers to HIV testing included workload and complex protocols.
- Legal restrictions and reimbursement issues were primary barriers to PrEP implementation.
- Potential solutions include collaborative agreements, standing orders, telePrEP integration, and champions.
Conclusions:
- Pharmacy-based HIV testing and PrEP initiation face significant implementation barriers.
- Addressing legal restrictions, reimbursement, and workflow integration is crucial for success.
- Tailored implementation strategies are needed to optimize sustainability and expand HIV services through pharmacies.
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