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Cutaneous extraskeletal Ewing's sarcoma.

M S Peters, H M Reiman, S A Muller

Journal of Cutaneous Pathology

|December 1, 1985

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Extraskeletal Ewing's sarcoma, a rare skin cancer, was identified in a 12-year-old girl. This case highlights the importance of considering this diagnosis for unusual cutaneous small cell tumors.

Area of Science:

Oncology
Dermatopathology
Pediatric Oncology

Background:

Extraskeletal Ewing's sarcoma (EES) is typically found in deep soft tissues.
Cutaneous EES is an exceptionally rare presentation of this bone and soft tissue malignancy.

Observation:

A 12-year-old girl presented with a dermal and subcutaneous tumor on her left third toe.
The tumor showed no bone involvement, indicating a primary cutaneous origin.

Findings:

Histopathology revealed masses of round-oval cells with features typical of Ewing's sarcoma, including glycogen in the cytoplasm.
Ultrastructural analysis confirmed a monotonous cell population with specific ultrastructural markers.

Implications:

This case underscores the rarity of cutaneous EES and the diagnostic challenges it presents.

Related Experiment Videos

Accurate differential diagnosis is crucial for managing small cell malignancies of the skin.