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Updated: Sep 12, 2025

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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
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Semi-automated topic identification for radiation oncology safety event reports using natural language processing and
Qian Sophia Zhang1, John Kang2, Kevin Lybarger3
1Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Medical Physics
|August 9, 2025
Summary
A new semi-automated method effectively categorizes Radiation Oncology safety reports. This approach expedites analysis and identifies novel safety topics, improving incident learning.
Area of Science:
- Medical Physics
- Health Informatics
- Radiation Oncology
Background:
- Incident learning in healthcare generates valuable safety and quality data.
- Analyzing large volumes of unstructured text data from incident reports is challenging.
Purpose of the Study:
- To develop and validate a semi-automated method for categorizing safety-related event reports.
- To apply this method to Radiation Oncology safety reports.
Main Methods:
- A correlated topic model (CTM) with 50 topics was fitted to 7174 safety-related event reports from a Radiation Oncology department (2012-2021).
- Expert validation involved assigning consensus topic labels (CTLs) using a "top-10 tokens" approach and a "case-reports" approach (reports ≥90% about a topic).
Main Results:
- The model's validity was supported, with 74% (37/50) of topics achieving majority expert agreement on CTL assignment.
- The "top-10 tokens" approach assigned CTLs to 36 topics, while the "case-reports" approach assigned CTLs to 18 of 20 applicable topics.
- Seven novel safety topics were identified that were not previously discovered through manual review.
Conclusions:
- A semi-automated method can effectively categorize Radiation Oncology safety-related event reports by topic.
- This method offers a faster alternative to manual review of numerous reports.
- The approach facilitates the discovery of previously unidentified safety topics.
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