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Oral cancer detection via Vanilla CNN optimized by improved artificial protozoa optimizer
Yulong Chai1, Xiuqing Chai2, Lan Zhang1
1Lin'an Oral Hospital, Hangzhou, 311300, Zhejiang, China.
Scientific Reports
|August 9, 2025
Summary
A novel method enhances oral cancer detection using an Improved Artificial Protozoa Optimizer (IAPO) to optimize a modified Vanilla Convolutional Neural Network (CNN). This approach achieves 92.5% accuracy, outperforming existing models for reliable oral cancer diagnosis.
Area of Science:
- Medical Imaging and Diagnostics
- Artificial Intelligence in Healthcare
- Computational Biology
Background:
- Oral cancer detection remains a critical challenge in healthcare, necessitating advanced diagnostic tools.
- Existing deep learning models show promise but require further optimization for improved accuracy and reliability.
- Metaheuristic algorithms offer potential for fine-tuning complex neural network architectures.
Purpose of the Study:
- To develop and evaluate a novel, optimized Convolutional Neural Network (CNN) for enhanced oral cancer detection.
- To introduce an Improved Artificial Protozoa Optimizer (IAPO) for optimizing the CNN architecture.
- To compare the proposed method's performance against established state-of-the-art models.
Main Methods:
- A modified Vanilla CNN architecture was designed, incorporating batch normalization, dropout regularization, and a custom convolutional block.
- The Improved Artificial Protozoa Optimizer (IAPO) algorithm was developed and employed to optimize the Vanilla CNN parameters.
- A dataset of 1000 oral cancer patient images underwent preprocessing, including contrast enhancement, noise reduction, and data augmentation.
Main Results:
- The IAPO-optimized Vanilla CNN achieved a high accuracy of 92.5% in oral cancer detection.
- Performance was superior to ResNet-101 (90.1%) and DenseNet-121 (89.5%).
- Evaluated using standard metrics: accuracy, precision, recall, F1-score, and AUC-ROC.
Conclusions:
- The proposed IAPO-optimized Vanilla CNN presents a highly accurate and trustworthy method for oral cancer detection.
- The IAPO algorithm effectively optimizes CNNs, demonstrating superior search space exploration and avoidance of local optima.
- This advanced approach holds significant potential for improving early diagnosis and patient outcomes in oral oncology.

