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Neoadjuvant Immune Checkpoint Inhibitors in CSCC: A Systematic Review and Meta-Analysis

Valbert Oliveira Costa Filho1, Mariana Macambira Noronha1, Pedro Robson Costa Passos2

  • 1Biomedical Research Center (NUBIMED), Federal University of Ceara, Fortaleza, Ceara, Brazil.

Journal of Cutaneous Medicine and Surgery
|August 11, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
checkpoint inhibitorcutaneous squamous cell carcinomameta-analysisneoadjuvantnonmelanoma skin cancer

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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