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Ovarian Cystadenofibroma: An Overview
1Obstetrics and Gynaecology, Apollo Hospitals, Chennai, IND.
Cureus
|August 11, 2025
Summary
Ovarian cystadenofibromas, though benign, are increasingly seen and can mimic malignancy. Understanding their subtypes and clinical patterns aids in appropriate surgical planning and avoids overtreatment.
Area of Science:
- Gynecologic Oncology
- Pathology
- Epidemiology
Background:
- An increasing frequency of ovarian cystadenofibromas, a benign tumor with cystic and solid features, was observed.
- These tumors can present asymptomatically or with abdominal/menstrual irregularities, necessitating clinical investigation.
Purpose of the Study:
- To investigate the clinical and epidemiological patterns of ovarian cystadenofibromas.
- To identify associations between histological subtypes and clinical presentation.
Main Methods:
- A retrospective observational study of 96 ovarian cystadenofibroma cases operated between January 2023 and November 2023.
- Assessment of demographic, clinical, radiological, intraoperative, and histopathological findings.
Main Results:
- Serous (44%), mucinous (38%), and mixed (19%) subtypes were identified.
- Significant associations were found between subtype and dyslipidaemia, heavy menstrual bleeding, dysmenorrhea, infertility, tumor size, laterality, and torsion.
- Mixed tumors were larger and more prone to torsion; serous tumors showed more bilateral involvement.
Conclusions:
- A higher than expected number of cystadenofibromas were observed.
- These benign tumors can mimic malignancy, potentially leading to aggressive surgery.
- Early identification and correlation can reduce overtreatment and guide surgical planning.
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