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Related Concept Videos

Fractures: Bone Repair01:27

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
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Related Experiment Video

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Knee Arthrocentesis in Adults
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Intra-Articular Steroid Hip Injections Association with Fracture: A Case Series.

Ajay Nair1, Jacob S Alexander2, Carter Bench2

  • 1Department of Orthopaedic Surgery University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.

Journal of Orthopaedic Case Reports
|August 11, 2025
PubMed
Summary

Corticosteroid injections (CSIs) for osteoarthritis may increase the risk of femoral neck fractures (FNFs) shortly after the procedure. This case series suggests a potential link, warranting further investigation into the bone health effects of intra-articular steroids.

Keywords:
Steroidsbonefemurfractureintra-articularosteoarthritis

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Area of Science:

  • Orthopedics
  • Rheumatology
  • Bone Health

Background:

  • Osteoarthritis (OA) is a prevalent orthopedic condition globally.
  • Corticosteroid injections (CSIs) are a common treatment for OA, but their effects on bone health remain debated.
  • Some evidence suggests CSIs may have detrimental effects on bone, including degeneration and fracture risk.

Observation:

  • This case series describes three patients of varying ages who experienced femoral neck fractures (FNFs) after intra-articular corticosteroid injections for hip OA.
  • All fractures occurred after ground-level falls within 4 to 32 days post-injection.
  • The fractures included two right subcapital FNFs and one left transcervical fracture.

Findings:

  • The study highlights a potential association between intra-articular CSIs and subsequent FNFs.
  • Corticosteroids are known to contribute to osteoporosis, a condition that weakens bones.
  • The findings suggest that the immunosuppressive effects of CSIs might compromise bone integrity.

Implications:

  • The decision to use intra-articular CSIs should be individualized, considering potential risks to bone health.
  • Further research is crucial to elucidate the relationship between CSIs and FNF risk.
  • Increased awareness and investigation into the bone-related side effects of intra-articular steroid injections are warranted.