Right Ventricular Outflow Tract Mass in Antiphospholipid Syndrome

Area of Science:

• Cardiology
• Rheumatology
• Hematology

Background:

• Antiphospholipid syndrome (APS) is characterized by recurrent arterial and venous thrombosis.
• Intracardiac thrombosis is a known, though less common, manifestation of APS, typically affecting the right atrium.
• Thrombosis in the right ventricular outflow tract (RVOT) is an exceptionally rare presentation of APS.

Purpose of the Study:

• To report a unique case of Antiphospholipid Syndrome presenting with thrombosis in the right ventricular outflow tract (RVOT).
• To illustrate the potential for regression of intracardiac thrombosis in APS with appropriate management.
• To highlight the importance of considering rare thrombotic locations in APS diagnosis and treatment.

Main Methods:

• Case report of a patient diagnosed with Antiphospholipid Syndrome.
• Diagnostic imaging to identify intracardiac thrombosis.
• Treatment with aggressive anticoagulation therapy.

Main Results:

• A patient with Antiphospholipid Syndrome developed a significant thrombosis within the right ventricular outflow tract (RVOT).
• The intracardiac thrombosis demonstrated complete regression following intensive anticoagulation treatment.
• No major adverse cardiovascular events occurred during the treatment period.

Conclusions:

• Right ventricular outflow tract (RVOT) thrombosis can be a manifestation of Antiphospholipid Syndrome.
• Aggressive anticoagulation is an effective treatment strategy for RVOT thrombosis in APS.
• Early diagnosis and management are crucial for favorable outcomes in complex APS cases.