Multicenter evaluation of the color vision screener test

Area of Science:

• Ophthalmology
• Optometry
• Vision Science

Background:

• Congenital color vision deficiency affects a significant portion of the population.
• Accurate and efficient screening tools are crucial for early detection and management.
• Existing screening methods have varying levels of accuracy and usability.

Purpose of the Study:

• To evaluate the diagnostic performance of the Color Vision Screener (CVS) test.
• To compare the CVS test against the established Colour Assessment and Diagnosis (CAD) test.
• To determine the sensitivity, specificity, and predictive values of the CVS test.

Main Methods:

• An international multicenter study involving over 400 participants.
• Participants included normal trichromats and individuals with congenital color vision deficiencies.
• The CVS test and the CAD test were administered on calibrated visual displays.

Main Results:

• The CVS test achieved a sensitivity of 1.00 (95% CI: 0.98-1.00) and specificity of 0.99 (95% CI: 0.97-1.00).
• Positive predictive index was 0.94 and negative predictive index was 1.00 for an 8% prevalence.
• The CVS test demonstrated performance equivalent to the optimal Ishihara protocol.

Conclusions:

• The Color Vision Screener (CVS) is a highly accurate tool for detecting congenital color vision deficiencies.
• The CVS test is quick, efficient, and easy to use, making it suitable for widespread screening.
• Its performance is comparable to established gold-standard tests, offering a reliable alternative.