A scoping review protocol: Neuropsychological development in pediatric ophthalmology patients with social

Euna Cho1, Justin Zhang1, Rebecca Li2

  • 1Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.

Plos One
|August 12, 2025
PubMed

Insights

Social determinants of health significantly impact pediatric ocular diseases and their effects on neuropsychological development. This review examines how environmental factors influence these outcomes, aiming to reduce health disparities.

Area of Science:

  • Ophthalmology
  • Neuropsychology
  • Public Health
  • Health Disparities

Background:

  • Ocular diseases present a global health burden, particularly affecting pediatric neuropsychological development, impacting academics, social skills, and mental well-being.
  • Neuropsychological development is crucial for cognitive function, emotional regulation, social interaction, and long-term health.
  • Social determinants of health (SDOH) can exacerbate the negative effects of ocular diseases on children's development, leading to disparities.

Purpose of the Study:

  • To conduct a scoping review evaluating the influence of social determinants of health (SDOH) on the impact of ocular diseases on pediatric neuropsychological development.
  • To identify how environmental and socioeconomic factors modulate the relationship between ocular conditions and developmental outcomes in children.

Main Methods:

  • A comprehensive literature search will be conducted across multiple databases (Cochrane, Embase, Europe PMC, Medline, PsycInfo, Scopus).
  • Inclusion criteria include ocular disease, neuropsychological development, pediatric population, and social determinants of health.
  • Articles will be screened using Covidence software and classified by national income, healthcare index, ocular disease type, neuropsychological category, and SDOH domain.

Main Results:

  • Quantitative analysis will report the percentage classification of articles across ocular, neuropsychological, and SDOH domains.
  • Sub-categorization will analyze article counts by national location, income level, and universal healthcare presence within explored SDOH domains.

Conclusions:

  • This scoping review will elucidate the complex interplay between SDOH, ocular diseases, and pediatric neuropsychological development.
  • Findings aim to inform strategies for mitigating health disparities and improving developmental outcomes for affected children.
Abstract

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