Related Experiment Video
Updated: Sep 11, 2025

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
Published on: October 11, 2024
Alveolar cleft repair: A 30-year follow-up
Rossella Elia1, Giuseppe Giudice1, MIchele Maruccia1
1U.O.C. Chirurgia Plastica, Ricostruttiva ed Estetica, Dipartimento di Medicina di Precisione e Rigenerativa e Area Jonica, Università̀ degli Studi di Bari Aldo Moro, A.O.C. Policlinico di Bari, Bari, Italy.
Secondary alveolar bone grafting (SABG) provides lasting benefits for cleft lip and palate patients over 30 years. Good oral health and orthodontic care are key predictors of successful outcomes and improved quality of life.
Area of Science:
- Craniofacial surgery
- Pediatric dentistry
- Orthodontics
Background:
- Secondary alveolar bone grafting (SABG) is crucial for cleft lip and palate (CLP) management.
- Long-term outcomes of SABG beyond ten years are not well-documented.
Purpose of the Study:
- To conduct a 30-year longitudinal evaluation of SABG outcomes in complete unilateral non-syndromic CLP.
- To identify clinical, radiological, and patient-reported predictors of surgical success.
Main Methods:
- Retrospective cohort analysis of 32 patients who underwent SABG (1990-1994).
- Clinical assessment (DMFT index), radiological assessment (Cone Beam CT, Suomalainen Index), and patient-reported outcomes (CLEFT-Q).
- Uni- and multivariate regression analyses for outcome predictors.
Main Results:
- 56.3% achieved satisfactory radiological outcomes (Suomalainen Index ≥12) after 30 years.
- Autologous grafting, good oral health (low DMFT), and orthodontic compliance were associated with favorable outcomes.
- Oral health and orthodontic treatment were independent predictors in multivariate analysis.
Conclusions:
- SABG offers durable clinical and radiological benefits for over three decades.
- Optimal outcomes depend on orthodontic management and sustained oral health.
- Successful grafts correlate with improved patient satisfaction and psychosocial well-being.
More Related Videos
04:17Author Spotlight: Development and Evaluation of a Standardized Rat Model for Calvarial Suture-Bony Composite Defects
Published on: May 10, 2024
10:30Author Spotlight: Developing a Microfluidic Lung-on-Chip Model for In-Depth Study of Human Immune Response and Infection Mechanisms
Published on: May 31, 2024