Related Experiment Video
Updated: Sep 11, 2025

Integrated Compensatory Responses in a Human Model of Hemorrhage
Published on: November 20, 2016
Making the invisible visible: exploring cardiovascular regulation with a simple analog blood pressure model
Heidi L Lujan1, Stephen E DiCarlo1
1Department of Physiology, College of Osteopathic MedicineMichigan State University, East Lansing, Michigan, United States.
None:
Blood pressure regulation keeps us alive, yet its underlying mechanisms often remain abstract for students. Heart rate, stroke volume, vascular resistance, and compliance interact continuously to shape arterial pressure, but in many classrooms, these variables feel disconnected from observable outcomes. To bridge this gap, we developed a simple, low-cost analog model that allows learners to manipulate key cardiovascular parameters and immediately observe the results. The model consists of a hand-operated bicycle pump (heart), 60-mL syringe (compliance chamber), adjustable clamp (vascular resistance), manometer (arterial pressure), and transparent flow reservoir. Together, these components externalize normally hidden variables, allowing students to explore how changes in cardiac output, resistance, and compliance alter pressure waveforms and flow dynamics in real time. The flow reservoir provides intuitive visual feedback: high compliance produces steady, laminar bubble flow, whereas low compliance generates phasic, turbulent flow. The model was implemented in large-group classroom demonstrations and small-group laboratory sessions. Across settings, students reported increased understanding and engagement, while instructors observed enhanced mechanistic reasoning and conceptual clarity. The model is affordable and reusable and requires no animal use, making it adaptable for a wide range of educational environments. By making the invisible visible, this model transforms cardiovascular physiology from abstract theory into an interactive, accessible learning experience.NEW & NOTEWORTHY This simple, hands-on model lets students take control of the cardiovascular system, adjusting heart rate, stroke volume, resistance, and compliance, and immediately see how pressure and flow respond. Built from inexpensive materials, it transforms abstract hemodynamic principles into visible, interactive outcomes. By making the invisible visible, this model sparks curiosity, promotes mechanistic reasoning, and brings cardiovascular physiology to life in classrooms and labs.
Related Concept Videos
Neural Regulation of Blood Pressure
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
Hypertension and Regulation of Blood Pressure
Regulation of the Cardiovascular System
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
Pre-Procedural Guidelines for Assessing Blood Pressure
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
Measurement of Blood Pressure

