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Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

532
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
532
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

600
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
600

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Related Experiment Video

Updated: Sep 11, 2025

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
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Chemical sensing as a utility using parallel, distributed swept source Raman spectroscopy.

Nili Persits, Dahlia L Dry, Jaehwan Kim

    Optics Express
    |August 13, 2025
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a distributed Raman spectroscopy network using optical fibers, enabling scalable, remote molecular analysis. This novel approach enhances accessibility and resource sharing for industrial and environmental monitoring.

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    Area of Science:

    • Analytical Chemistry
    • Spectroscopy
    • Biotechnology

    Background:

    • Current molecular analysis methods lack accessibility and scalability.
    • Existing approaches involve sample transportation or isolated analyzers.
    • Modern infrastructure demands more integrated and distributed sensing solutions.

    Purpose of the Study:

    • To develop a novel parallel, distributed optical fiber swept-source Raman spectroscopy approach.
    • To create a scalable network of remote Raman sensors.
    • To demonstrate the network's utility in industrial and environmental monitoring.

    Main Methods:

    • Utilized compact semiconductor tunable lasers and high-collection power fiber-optic probes.
    • Integrated sensitive single photon avalanche detectors (SPAD).
    • Deployed a network of Raman sensors across 16 locations (100 m distances), sharing resources like lasers and leveraging existing fiber optics.

    Main Results:

    • Achieved a scalable network of distributed Raman sensors.
    • Fiber probes demonstrated 12x higher light collection power than benchtop spectrometers.
    • Successfully monitored monoclonal antibody production and nitrogen fertilizer levels.

    Conclusions:

    • The developed distributed Raman spectroscopy network offers enhanced accessibility and scalability.
    • This approach integrates well with existing infrastructure for resource sharing.
    • The system is effective for real-time industrial and environmental monitoring applications.