Synchronized RF and HIFES Technology for Clinically Significant Wrinkle Reduction: A Multicenter 3D Evaluation.

Area of Science:

• Aesthetic dermatology and cosmetic procedures.
• Energy-based devices for skin rejuvenation.

Background:

• Youthful skin is associated with health and well-being.
• Noninvasive energy-based procedures are popular for targeting aging signs through controlled stimulation.

Purpose of the Study:

• To evaluate High-Intensity Focused Electrical Stimulation (HIFES) combined with synchronized radiofrequency (RF) for noninvasive wrinkle treatment.

Main Methods:

• Thirty-three patients received four HIFES and synchronized RF treatments.
• Objective wrinkle assessment using 3D and 2D photography (GAIS, FWES).
• Subjective patient outcomes via satisfaction and comfort surveys.

Main Results:

• Significant wrinkle reduction observed, with 3D analysis showing up to 35.36% improvement at 3 months.
• 88% of participants showed improvement on the Global Aesthetic Improvement Scale (GAIS) at 3 months.
• High patient satisfaction and comfort reported, with a shift in wrinkle severity classification.

Conclusions:

• HIFES combined with synchronized RF is an effective noninvasive wrinkle treatment.
• The procedure demonstrates objective efficacy and positive patient-reported outcomes.
• Offers a safe and well-tolerated option for enhancing skin appearance and quality.