Related Experiment Video
Updated: Jul 6, 2026

07:45
An Explant Assay for Assessing Cellular Behavior of the Cranial Mesenchyme
Published on: January 20, 2013
9.9K
ICL Exchanges or Explants Due to Sizing in a United States High Volume Center.
Matthew Hirabayashi1, Gurpal Virdi2, Taj Nasser3
1Parkhurst NuVision LASIK Eye Surgery, San Antonio, TX, USA.
Clinical Ophthalmology (Auckland, N.Z.)
|August 13, 2025
Summary
Implantable Collamer Lens (ICL) exchange is rare, occurring in 1.1% of cases due to sizing or rotation issues. This indicates ICL surgery is safe with a low complication rate.
Area of Science:
- Ophthalmology
- Refractive Surgery
Background:
- Implantable Collamer Lens (ICL) is a popular choice for vision correction.
- Understanding ICL exchange rates is crucial for assessing safety and outcomes.
Purpose of the Study:
- To determine the incidence, reasons, and outcomes of ICL exchanges.
- To analyze ICL exchange cases at a high-volume US center.
Main Methods:
- Retrospective chart review of 961 eyes undergoing ICL surgery.
- Analysis of cases requiring ICL exchange between April 2022 and October 2024.
Main Results:
- An overall ICL exchange rate of 1.1% (11 eyes) was observed.
- Sizing issues accounted for 1.1% of exchanges, with vault concerns in 0.5% and toric ICL rotation in 0.6%.
- Re-evaluation suggested alternative sizing in 3 of the exchange cases.
Conclusions:
- ICL implantation demonstrates high safety with a very low exchange rate due to sizing.
- Most exchanges were linked to toric ICL rotation, not vault issues.
- The study reinforces the safety profile of ICLs in refractive surgery.

